26321-29-9

Basic information

• Product Name: Benzene, 1-methoxy-2-(2-methylphenoxy)-
• CAS NO: 26321-29-9
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Mol File: 26321-29-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-2-(2-methylphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-2-(2-methylphenoxy)-(26321-29-9)
• EPA Substance Registry System: Benzene, 1-methoxy-2-(2-methylphenoxy)-(26321-29-9)

Safety Data

• Hazardous Substances Data: 26321-29-9(Hazardous Substances Data)

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 90-05-1 2-methoxy-phenol 
• 16419-60-6 2-Methylphenylboronic acid 
• 95-46-5 2-methylphenyl bromide 
• 578-57-4 2-bromoanisole 
• 95-48-7 ortho-cresol 

Downstream Products

• 3487-81-8 2-(2-hydroxy-phenoxy)-benzoic acid 
• 21905-73-7 2-carboxy-2'-methoxydiphenyl ether 

Relevant articles and documents

Solvent-free palladium-catalyzed C–O cross-coupling of aryl bromides with phenols

A new solvent-free procedure for C–O cross-coupling between phenols and aryl bromides comprising of Pd2(dba)3/ButBrettPhos catalytic system is efficient for substrates bearing donor or acceptor, as well as bulky substituents.

Cu-catalyzed arylation of phenols: Synthesis of sterically hindered and heteroaryl diaryl ethers

"Chemical Equation Presentation" Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl ethers.

Bio-inspired copper catalysts for the formation of diaryl ethers

Aryl bromides and phenols are coupled efficiently to the corresponding diaryl ethers in the presence of a practical Cu(I)/1-butylimidazole catalyst system. The convenient protocol is applied successfully to the synthesis of 16 different diaryl ethers in high yield and selectivity.