263269-69-8

Basic information

• Product Name: N-{4-methyl-3-[4-(2-methylthiazol-4-ylmethoxy)benzamido]phenyl}-2-morpholinopyridine-4-carboxamide
• CAS NO: 263269-69-8
• Molecular Weight: 543.646
• Mol File: 263269-69-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{4-methyl-3-[4-(2-methylthiazol-4-ylmethoxy)benzamido]phenyl}-2-morpholinopyridine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-methyl-3-[4-(2-methylthiazol-4-ylmethoxy)benzamido]phenyl}-2-morpholinopyridine-4-carboxamide(263269-69-8)
• EPA Substance Registry System: N-{4-methyl-3-[4-(2-methylthiazol-4-ylmethoxy)benzamido]phenyl}-2-morpholinopyridine-4-carboxamide(263269-69-8)

Safety Data

• Hazardous Substances Data: 263269-69-8(Hazardous Substances Data)

Upstream product

• 263270-62-8 4-(2-methylthiazol4-ylmethoxy)benzoic acid 
• 258503-86-5 N-(3-amino-4-methylphenyl)-2-morpholinopyridine-4-carboxamide 

Relevant articles and documents

BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS

The invention concerns amide derivatives of formula (I) wherein R 3 is (1-6C)alkyl or halogeno; m is 0-3, p is 0-2 and q is 0-4; each of R 1 and R 2 is a group such as hydroxy, halogeno, trifluoromethyl and cyano; R 4 is a basic group such as amino, (1-6C)alkylamino, di-[(1-6C)alkyl]amino, di-[(1-6C)alkyl]amino-(1-6C)alkyl, di-[(1-6C)alkyl]amino-(2-6C)alkoxy, heteroaryl, heteroaryloxy, heteroaryl-(1-6C)alkoxy, heterocyclyl, heterocyclyloxy and heterocyclyl-(1-6C)alkoxy; and Q 2 is a group such as heteroaryl, heteroaryloxy or heteroaryl-(1-6C)alkoxy which is optionally substituted; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.