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11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE, also known as N-Desmethyl 8-Chloro-5H-dibenzo[b,e][1,4]diazepine, is a chemical compound that serves as an impurity in Clozapine (C587500), an antipsychotic medication. 11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE is characterized by its unique molecular structure, which includes a piperazine bridge connecting two dibenzodiazepine rings, with one of the rings bearing an 8-chloro substitution.

263366-81-0

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263366-81-0 Usage

Uses

Used in Pharmaceutical Industry:
11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE is used as an impurity in Clozapine, an antipsychotic medication, for the treatment of various psychiatric disorders. Its presence in Clozapine is significant as it can affect the drug's efficacy, safety, and quality. Monitoring and controlling the levels of this impurity in Clozapine is crucial to ensure the medication's therapeutic benefits and minimize potential side effects.
In the context of pharmaceutical research and development, understanding the properties and effects of 11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE can also contribute to the design and synthesis of new antipsychotic drugs with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 263366-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,3,3,6 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 263366-81:
(8*2)+(7*6)+(6*3)+(5*3)+(4*6)+(3*6)+(2*8)+(1*1)=150
150 % 10 = 0
So 263366-81-0 is a valid CAS Registry Number.

263366-81-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloro-6-[4-(3-chloro-5H-benzo[b][1,4]benzodiazepin-6-yl)piperazin-1-yl]-5H-benzo[b][1,4]benzodiazepine

1.2 Other means of identification

Product number -
Other names 11,11'-(Piperazine-1,4-diyl)-bis-8-chloro-5H-dibenze[b,e][1,4]-diazepine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:263366-81-0 SDS

263366-81-0Upstream product

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