263368-45-2Relevant academic research and scientific papers
Palladium-catalyzed synthesis of cephalotaxine analogues
Tietze, Lutz F.,Schirok, Hartmut,Woehrmann, Michael
, p. 510 - 518 (2007/10/03)
The synthesis of cephalotaxine ring analogues 10 was achieved by two successive intramolecular palladium-catalyzed reactions of 12 via 11, namely an allylic amination and a Heck reaction. The substrates 12 were obtained by alkylation of primary amines 13 with tosylates 14.
Efficient synthesis of six-membered ring D analogues of the pentacyclic alkaloid cephalotaxine by two palladium-catalyzed reactions
Tietze, Lutz F.,Schirok, Hartmut,Woehrmann, Michael,Schrader, Klaus
, p. 2433 - 2444 (2007/10/03)
D-homo-Cephalotaxine analogues 19 and 23 have been prepared by intramolecular Heck reactions of 12 and 22. The substrates 12 and 22 were obtained by alkylation and acylation, respectively, of the spirocyclic amines 17, which, in turn, were generated by in
