263386-45-4

Upstream product

• 10075-50-0 5-bromo-1H-indole 
• 200347-72-4 tert-butyl 2-(benzyl(hydroxy)amino)-2-(1H-indol-3-yl)ethylcarbamate 

Downstream Products

• 1044516-32-6 N-(benzylidene)-2-[N'-(tert-butoxycarbonyl)amino]-1-(5'-bromo-3'-indolyl)ethanamine N-oxide 
• 1419517-46-6 tert-butyl (2-benzamido-2-(5-bromo-1H-indol-3-yl)ethyl) carbamate 
• 1616790-08-9 tert-butyl (2-(1-benzyl-3-hydroxyureido)-2-(5-bromo-1H-indol-3-yl)ethyl)carbamate 
• 1044516-31-5 tert-butyl (2-(benzylamino)-2-(5-bromo-1H-indol-3-yl)ethyl)carbamate 

Relevant academic research and scientific papers

NOVEL BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG

The present invention relates to novel bis-indolic derivatives, processes for their preparation, and their potential use as new antibacterial drugs.

Novel bis-indolic derivatives, their uses in particular as antibacterials

The present invention relates to novel bis-indolic derivatives, processes for their preparation, and their potential use as new antibacterial drugs.

BIS-INDOLIC DERIVATIVES, THEIR USES IN PARTICULAR AS ANTIBACTERIALS

The present invention relates to novel bis-indolic derivatives, processes for their preparation, and their potential use as new antibacterial drugs.

BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG

The present invention relates to novel bis-indolic derivatives, processes for their preparation, and their potential use as new antibacterial drugs.

Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents

A collection of 3-substituted indole derivatives was prepared using nucleophilic addition of indoles to nitrones. The compounds were then tested for their antibacterial activity against almost thirty bacterial strains representative of common human pathog

NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS

The invention relates to the use of at least one compound of the formula (I), in which R and R3 are particularly a hydrogen atom, R1 is particularly a hydrogen atom or a methyl, ethyl or isobutyl mi group, R4, R5, R6 and R7 are independently a hydrogen atony, an alkoxyl group with 1 to 7 carbon atoms or a halogen atom, R2 is a hydrogen atom, an O? group or an OH group, B is an N-GP1 or NRc, group, GP1 being a Boc or Cbz group, and Rc is a hydrogen atom or a methyl or t-butyl group, for preparing a drug for treating conditions associated with bacterial infections, in particular for treating bacterial diseases.

The reactions of nitrones with indoles

The reaction of nitrones with various indole derivatives has been studied. When the reaction was promoted by C1SiMe3, the isolated products were 3,3'-diindolylalkanes. With HC1 as the activating reagent, 3- indolylhydroxylamines were isolated. The diastereoselectivity of this condensation with a nitrone derived from cysteine was investigated. A method for the introduction of an alkylhydroxylamino group onto position 2 of indole, the synthesis of three natural 3,3'-diindolylalkanes and of non- symmetric diindolylalkanes are also reported. (C) 2000 Elsevier Science Ltd.