263393-30-2

Upstream product

• 263393-45-9 3(S)-1-benzoyl-3-(3,4-difluorophenyl)-3-(formylmethyl)piperidine 
• 263393-50-6 4-(tetrahydropyran-4-yl)piperidine 

Relevant academic research and scientific papers

Substituted benzoylpiperidine derivatives and their use as Neurokinin antagonists

The present invention provides a compound of the formula:- or a pharmaceutically acceptable acid addition salt thereof, whereinAr is phenyl substituted by 1 or 2 substituent(s) each independently selected from fluoro and chloro;X is NSO2(C1-C4 alkyl), NSO2(halo(C1-C4 alkyl)) or O;m is 0 or 1 ;n is 1 or 2;p is 1 or 2;q is 1 or 2; and r is 1 or 2, together with processes for the preparation of, intermediates used in the preparation of, compositions containing and uses of, such derivatives. The compounds have tachykinin receptor antagonist activity.