263406-16-2Relevant academic research and scientific papers
Total synthesis of (±)-desoxycodeine-D: A novel route to the morphine skeleton
Liou, Jing-Ping,Cheng, Chen-Yu
, p. 915 - 918 (2000)
A novel approach towards the construction of the morphine skeleton was demonstrated by a total synthesis of (±)-desoxycodeine-D (11) from 5,6,7,8- tetrahydroisoquinoline and isovanillin. The key steps are two consecutive Pd- catalyzed cyclizations and a Stevens rearrangement for the formation of ring B. (C) 2000 Elsevier Science Ltd.
