26342-05-2

Basic information

• Product Name: ETHYL 5-AMINOVALERATE
• Synonyms: Valericacid, 5-amino-, ethyl ester (6CI,7CI,8CI);Ethyl 5-aminopentanoate;Ethyl 5-aminovalerate;5-Aminovaleric acid ethyl ester;5-Aminopentanoic acid ethyl ester
• CAS NO: 26342-05-2
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.20
• Mol File: 26342-05-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 190.398 °C at 760 mmHg
• Flash Point: 62.01 °C
• Appearance: /
• Density: 0.96 g/cm³
• Vapor Pressure: 0.542mmHg at 25°C
• Refractive Index: 1.439
• CAS DataBase Reference: ETHYL 5-AMINOVALERATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-AMINOVALERATE(26342-05-2)
• EPA Substance Registry System: ETHYL 5-AMINOVALERATE(26342-05-2)

Safety Data

• Hazardous Substances Data: 26342-05-2(Hazardous Substances Data)

Usage

General Description

ETHYL 5-AMINOVALERATE, also known as 5-Aminovaleric acid ethyl ester, is a chemical compound with the molecular formula C7H15NO2. It is an ester of the amino acid 5-aminovaleric acid and ethyl alcohol. ETHYL 5-AMINOVALERATE is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and medications. It is also utilized in the production of flavors and fragrances due to its pleasant odor. Additionally, ethyl 5-aminovalerate has been studied for its potential physiological and pharmacological effects, including its role in neurotransmitter modulation and its potential as a therapeutic agent for various health conditions.

InChI:InChI=1/C7H15NO2/c1-2-10-7(9)5-3-4-6-8/h2-6,8H2,1H3

Upstream product

• 626-86-8 adipinic acid monoethyl ester 
• 64-17-5 ethanol 
• 660-88-8 5-aminopentanoic acid 

Downstream Products

• 56753-66-3 C₁₅H₂₀N₂O₅S 
• 1620891-29-3 ethyl 5-(4-(2,3-dihydro-1H-perimidin-2-yl)benzamido)pentanoate 
• 102165-85-5 5-(5-phenylsulfanylcarbonylamino-valerylamino)-valeric acid ethyl ester 
• 101591-13-3 5-(5-phenylsulfanylcarbonylamino-valerylamino)-valeric acid 
• 100391-33-1 5-phenylsulfanylcarbonylamino-valeric acid 
• 101275-67-6 N-(5-phenylsulfanylcarbonylamino-valeryl)-alanine methyl ester 
• 56753-40-3 C₁₇H₂₄N₂O₅S 
• 101115-47-3 5-phenylsulfanylcarbonylamino-valeric acid ethyl ester 

Relevant articles and documents

Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma

Multiple myeloma (MM) is the second most common haematological malignancy. Almost all patients with MM eventually relapse, and most recommended treatment protocols for the patients with relapsed refractory MM comprise a combination of drugs with different mechanisms of action. Therefore novel drugs are in urgent need in clinic. Bcl-2 inhibitors and HDAC inhibitors were proved their anti-MM effect in clinic or under clinical trials, and they were further discovered to have synergistic interactions. In this study, a series of Bcl-2/HDAC dual-target inhibitors were designed and synthesized. Among them, compounds 7e–7g showed good inhibitory activities against HDAC6 and high binding affinities to Bcl-2 protein simultaneously. They also displayed good growth inhibitory activities against human MM cell line RPMI-8226, which proved their potential value for the treatment of multiple myeloma.