263545-00-2Relevant academic research and scientific papers
Synthesis of 4-arylsulfonylquinolines by double condensation of allyl aryl sulfones with nitroarenes
Wrobel, Zbigniew
, p. 521 - 525 (2007/10/03)
Allyl aryl sulfones 2 react with aryl nitrocompounds 1 in a DBU/MgCl2 system giving the 4-arylsulfonyl quinolines 3. Some mechanistic aspects of the reaction are discussed. Application of this reaction to the formal total synthesis of the natural product (-)-Eupolauramine is described.
