263552-81-4

Basic information

• Product Name: 1,3-Dibutyl-7-(3-chloropropylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1,3-Dibutyl-7-(3-chloropropylsulfonyl)xanthine
• CAS NO: 263552-81-4
• Molecular Formula: C₁₆H₂₅ClN₄O₄S
• Molecular Weight: 404.91905
• Mol File: 263552-81-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Dibutyl-7-(3-chloropropylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dibutyl-7-(3-chloropropylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione(263552-81-4)
• EPA Substance Registry System: 1,3-Dibutyl-7-(3-chloropropylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione(263552-81-4)

Safety Data

• Hazardous Substances Data: 263552-81-4(Hazardous Substances Data)

Upstream product

• 1633-82-5 3-chloro-n-propanesulfonyl chloride 
• 2850-36-4 1,3-dibutylxanthine 

Relevant articles and documents

Method of treating bone loss by stimulation of calcitonin

Compounds of the formula R1and R2are independently alkyl of 1 to 6 carbon atoms, allyl, or substituted allyl of 3 to 6 carbon atoms; R3is hydrogen, alkyl of 1 to 6 carbon atoms, or cycloalkyl of 3 to 10 carbon atoms; and R4is phenyl or naphthyl substituted with alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms or NR5R6; substituted or unsubstituted phenylalkyl wherein the alkyl group contains 1 to 6 carbon atoms; substituted or unsubstituted 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from N, S and O; substituted or unsubstituted cycloalkyl of 3 to 10 carbon atoms; or substituted or unsubstituted cycloalkylalkyl of 4 to 10 carbon atoms; provided that phenyl or naphthyl is substituted with NR5R6when R1and R2 is alkyl, are useful in the treatment of various disorders associated bone loss by increased transcription and elevation of plasma calcitonin levels. Such disorders include, but are not limited to: Paget's Disease, post menopausal osteoporosis, senile osteoporosis, and glucocorticoid-induced osteoporosis.