263706-70-3

Upstream product

• 1443157-16-1 ethyl 5-hydrazinyl-1,2,3-thiadiazole-4-carboxylate hydrochloride 
• 122-00-9 para-methylacetophenone 
• 6702-95-0 ethyl 5‐chloro‐1,2,3‐thiadiazole‐4‐carboxylate 

Downstream Products

• 263706-72-5 ethyl 6-(4-methylphenyl)-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine-3-carboxylate 
• 1350901-46-0 6-(4-methylphenyl)-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine-3-carbonyl chloride 
• 1350901-57-3 6-(4-methylphenyl)-3-[N-(4-methoxyphenyl)carbamoyl]-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine 
• 1350901-55-1 3-(N-benzylcarbamoyl)-6-(4-methylphenyl)-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine 
• 1350901-53-9 3-[N-(2-hydroxyethyl)carbamoyl]-6-(4-methylphenyl)-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine 
• 1350901-51-7 isoamyl 6-(4-methylphenyl)-5H-[1,2,3]triazolo[5,1-b][1,3,4]thiadiazine-3-carboxylate 

Relevant academic research and scientific papers

Synthesis of 5-(pyrazol-1-yl)-1,2,3-thiadiazoles

[Figure not available: see fulltext.] A method is proposed for the synthesis of ethyl 5-(3-aryl-4-formyl-1H-pyrazol-1-yl)-1,2,3-thiadiazole-4-carboxylates by a reaction of acetophenone (4-ethoxycarbonyl-1,2,3-thiadiazol-5-yl)hydrazones with a Vilsmeier–Haack complex. The obtained heterocyclic assemblies provide interesting substrates for further modification and study of biological activity.