263763-65-1Relevant academic research and scientific papers
Forskolin studies
Behnke, Dirk,Hennig, Lothar,Findeisen, Matthias,Welzel, Peter,Müller, Dietrich,Thormann, Michael,Hofmann, Hans-J?rg
, p. 1081 - 1095 (2007/10/03)
A new nucleophilic isoprenoid C5 reagent is introduced which allowed synthesis of an advanced and optically active forskolin intermediate in a very efficient way. In addition, docking experiments that are based on X-ray results indicate that there might exist forskolin analogues with improved properties as far as binding to adenylyl cyclases and synthetic accessibility are concerned. (C) 2000 Elsevier Science Ltd.
