263764-91-6

Basic information

• Product Name: 3-(3,4-dimethoxyphenyl)-4-hydroxyfuran-2(5H)-one
• Synonyms: 3-(3,4-dimethoxyphenyl)-4-hydroxyfuran-2(5H)-one
• CAS NO: 263764-91-6
• Molecular Weight: 236.224
• Mol File: 263764-91-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-(3,4-dimethoxyphenyl)-4-hydroxyfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dimethoxyphenyl)-4-hydroxyfuran-2(5H)-one(263764-91-6)
• EPA Substance Registry System: 3-(3,4-dimethoxyphenyl)-4-hydroxyfuran-2(5H)-one(263764-91-6)

Safety Data

• Hazardous Substances Data: 263764-91-6(Hazardous Substances Data)

Upstream product

• 98026-98-3 3-Diazotetrahydrofuran-2,4-dione 
• 91-16-7 1,2-dimethoxybenzene 
• 96-35-5 glycolic acid methyl ester 
• 15964-79-1 methyl (3,4-dimethoxyphenyl)acetate 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 263765-03-3 toluene-4-sulfonic acid 4-(3,4-dimethoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-yl ester 
• 263764-92-7 (3,4-dimethoxyphenyl)acetic acid ethoxycarbonylmethyl ester 

Downstream Products

• 1375540-57-0 4-(2-chlorophenylamino)-3-(3,4-dimethoxyphenyl)furan-2(5H)-one 
• 1375540-58-1 4-(3-chlorophenylamino)-3-(3,4-dimethoxyphenyl)furan-2(5H)-one 
• 1375540-59-2 3-(3,4-dimethoxyphenyl)-4-(2-nitrophenylamino)furan-2(5H)-one 
• 1346463-88-4 3-(3,4-dimethoxyphenyl)-4-(2-methoxyphenylamino)furan-2(5H)-one 
• 1320275-56-6 3-(3,4-dimethoxyphenyl)-4-(2-(4-methylpiperazin-1-yl)ethoxy)furan-2(5H)-one 
• 1320275-55-5 3-(3,4-dimethoxyphenyl)-4-(2-(piperidin-1-yl)ethoxy)furan-2(5H)-one 
• 1320275-54-4 4-(2-(cyclohexylamino)ethoxy)-3-(3,4-dimethoxyphenyl)furan-2(5H)-one 
• 1320275-73-7 4-(2-bromoethoxy)-3-(3,4-dimethoxyphenyl)furan-2(5H)-one 
• 1275611-66-9 C₁₂H₁₁ClO₄ 
• 263764-95-0 3-(3,4-dimethoxyphenyl)-4-bromo-5H-furan-2-one 
• 263765-03-3 toluene-4-sulfonic acid 4-(3,4-dimethoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-yl ester 

Relevant articles and documents

Catalytic Undirected Intermolecular C-H Functionalization of Arenes with 3-Diazofuran-2,4-dione: Synthesis of 3-Aryl Tetronic Acids, Vulpinic Acid, Pinastric Acid, and Methyl Isoxerocomate

A variety of 3-aryl tetronic acids have been synthesized by an undirected, intermolecular C-H functionalization of arenes with 3-diazofuran-2,4-dione. This methodology featured as a key step in the synthesis of a series of naturally occurring 3-aryl-5-arylidene tetronic acids (pulvinates) from commercially available tetronic acid. Salient features of the pulvinic acid synthesis include a one-step, stereoselective synthesis of the C5 arylidene group and a single step introduction of the C3 aryl substituent.

Structure and antibacterial activity of 3-(3,4-dimethoxyphenyl) furan-2(5H)-ones

Crystalline hydrate of the title compound (5), C19H 26N2O5·2(H2O), was structurally characterized by single crystal X-ray diffraction. It crystallizes in monoclinic system space group P 21/c with a =

4-Alkoxy-3-arylfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: Synthesis, molecular docking and antibacterial evaluation

A series of novel 4-alkoxy-3-arylfuran-2(5H)-ones as tyrosyl-tRNA synthetase inhibitors were synthesized. Of these compounds, 3-(4-hydroxyphenyl)- 4-(2-morpholinoethoxy)furan-2(5H)-one (27) was the most potent. The binding model and structure-activity rel