263845-08-5Relevant academic research and scientific papers
3-Imidazolymethylaminophenylsulfonytetrahydroquinolines, a novel series of farnesyltransferase inhibitors
Ding, Charles Z.,Hunt, John T.,Ricca, Carol,Manne, Veeraswamy
, p. 273 - 275 (2007/10/03)
Design, synthesis and structure-activity relationship of a series of 3-imidazolylmethylaminophenylsulfonyltetrahydroquinolines as farnesyltransferase inhibitors are presented. A working pharmacophore of inhibiting farnesyltransferase by this series of inhibitors is proposed. (C) 2000 Elsevier Science Ltd. All rights reserved.
