263862-77-7Relevant articles and documents
Total Synthesis and Determination of the Absolute Configuration of Frondosin B
Masayuki, Inoue,Carson, Mattew W.,Frontier, Alison J.,Danishefsky, Samuel J.
, p. 1878 - 1889 (2007/10/03)
Two concise syntheses of (+/-)-frondosin B (1), an interleukin-8 receptor antagonist, have been achieved from commercially available 5-methoxysalicylaldehyde. The seven-membered ring in ketone 33, the common intermediate for both syntheses, was built by a