26389-59-3 Usage
Uses
Used in Pharmaceutical Industry:
N-PROPYLCYCLOPROPANECARBOXAMIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
N-PROPYLCYCLOPROPANECARBOXAMIDE is utilized as a building block in the creation of agrochemicals, playing a role in the formulation of pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Organic Synthesis:
As a versatile chemical intermediate, N-PROPYLCYCLOPROPANECARBOXAMIDE is employed in the synthesis of a range of organic compounds for various applications across different industries, including the production of specialty chemicals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 26389-59-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,3,8 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26389-59:
(7*2)+(6*6)+(5*3)+(4*8)+(3*9)+(2*5)+(1*9)=143
143 % 10 = 3
So 26389-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H13NO/c1-2-5-8-7(9)6-3-4-6/h6H,2-5H2,1H3,(H,8,9)
26389-59-3Relevant academic research and scientific papers
Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides
George, Tesmol G.,Johnsamuel, Jayaseharan,Delfin, Dawn A.,Yakovich, Adam,Mukherjee, Mitali,Phelps, Mitch A.,Dalton, James T.,Sackett, Dan L.,Kaiser, Marcel,Brun, Reto,Werbovetz, Karl A.
, p. 5699 - 5710 (2007/10/03)
N1-Phenyl-3,5-dinitro-N4,N4-di-n-propylsulfanilamide (1) and N1-phenyl-3,5-dinitro-N4,N4-di-n-butylsulfanilamide (2) show potent in vitro antimitotic activity against kinetoplastid parasites but display poor in vivo activity. Seventeen new dinitroaniline sulfonamide and eleven new benzamide analogs of these leads are reported here. Nine of the sulfonamides display in vitro IC50 values under 500 nM against African trypanosomes, and the most active antikinetoplastid compounds also inhibit the in vitro assembly of purified leishmanial tubulin with potencies similar to that of 2. While several of the potent compounds are rapidly degraded by rat liver S9 fractions in vitro, N1-(3-hydroxy)phenyl-3,5-dinitro-N4,N4-di-n-butylsulfanilamide (21) displays an IC50 value of 260 nM against African trypanosomes in vitro and is more stable than 2 in the in vitro metabolism assay.
