263890-70-6

Basic information

• Product Name: GR148672X
• Synonyms: GR148672X;4,4,4-Trifluoro-1-(2-thienyl)-1,2,3-butanetrione 2-[(3-methylphenyl)hydrazone]
• CAS NO: 263890-70-6
• Molecular Formula: C15H11F3N2O2S
• Molecular Weight: 340.3202496
• EINECS: -0
• Mol File: 263890-70-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: GR148672X(CAS DataBase Reference)
• NIST Chemistry Reference: GR148672X(263890-70-6)
• EPA Substance Registry System: GR148672X(263890-70-6)

Safety Data

• Hazardous Substances Data: 263890-70-6(Hazardous Substances Data)

Usage

General Description

GR148672X is a chemical compound that acts as a selective and potent inhibitor of the enzyme acetyl-CoA carboxylase (ACC). This enzyme plays a crucial role in fatty acid synthesis, and its inhibition by GR148672X leads to a decrease in fatty acid production. GR148672X has shown promising potential as a therapeutic agent for the treatment of metabolic disorders such as obesity, type 2 diabetes, and hyperlipidemia. In preclinical studies, GR148672X has demonstrated the ability to reduce body weight, improve insulin sensitivity, and lower plasma lipid levels. Its unique mechanism of action and favorable pharmacological profile make it a promising candidate for further development as a novel treatment for metabolic diseases.