263896-27-1Relevant articles and documents
Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens
Jarvest, Richard L.,Hibbs, Martin J.,Jaworski, Deborah D.,O'Hanlon, Peter J.,Pope, Andrew J.,Rittenhouse, Stephen,Sheppard, Robert J.,Slater-Radosti, Courtney,Worby, Angela,Berge, John M.,Berry, Valerie,Boyd, Helen F.,Brown, Murray J.,Elder, John S.,Forrest, Andrew K.,Fosberry, Andrew P.,Gentry, Daniel R.
, p. 1959 - 1962 (2002)
Potent nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase have been derived from a file compound high throughput screening hit. Optimized compounds show excellent antibacterial activity against staphylococcal and enterococcal pathogen
METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS
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Page/Page column 101-103; 108-109, (2010/02/14)
The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.