263914-93-8

Basic information

• Product Name: 4-(Dimethylphenylsilyl)-3-butyn-2-one
• Synonyms: 4-(Dimethylphenylsilyl)-3-butyn-2-one
• CAS NO: 263914-93-8
• Molecular Formula: C₁₂H₁₄OSi
• Molecular Weight: 202.32
• Mol File: 263914-93-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 251 ºC
• Flash Point: 106 ºC
• Appearance: /
• Density: 0.98
• Vapor Pressure: 0.0207mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 4-(Dimethylphenylsilyl)-3-butyn-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Dimethylphenylsilyl)-3-butyn-2-one(263914-93-8)
• EPA Substance Registry System: 4-(Dimethylphenylsilyl)-3-butyn-2-one(263914-93-8)

Safety Data

• Hazardous Substances Data: 263914-93-8(Hazardous Substances Data)

Usage

General Description

4-(Dimethylphenylsilyl)-3-butyn-2-one is a specific chemical compound containing a silyl group and an alkyne functional group. It is commonly used in organic synthesis as a reagent for the introduction of silyl groups into organic molecules. The presence of the silyl group in this compound makes it useful for protecting alcohol and amine functional groups during chemical reactions. In addition, the alkyne functional group can undergo various reactions to form new carbon-carbon bonds, making 4-(Dimethylphenylsilyl)-3-butyn-2-one a versatile building block for the synthesis of complex organic molecules. Overall, this compound is an important tool for chemists in the preparation of various organic compounds.

InChI:InChI=1/C12H14OSi/c1-11(13)9-10-14(2,3)12-7-5-4-6-8-12/h4-8H,1-3H3

Upstream product

• 17156-64-8 (dimethylphenylsilyl)acetylene 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 768-33-2 phenyldimethylsilyl chloride 
• 263914-55-2 (+/-)-2-[3-(dimethylphenylsilyl)-1-methyl-2-propynyloxy]tetrahydropyran 
• 115884-67-8 (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol 
• 23183-95-1 1-dimethylphenylsilyl-2-trimethylsilylacetylene 
• 75-36-5 acetyl chloride 

Downstream Products

• 460095-39-0 4-dimethylphenylsilyl-3-butyn-2-one phenylhydrazone 
• 56539-60-7 4-dimethylphenylsilyl-3-en-2-one 
• 387354-11-2 4-iodo-3-methyl-5-dimethylphenylsilyl-1-phenylpyrazole 
• 460095-29-8 3-methyl-5-dimethylphenylsilylisoxazole 
• 387354-05-4 1,3-dimethyl-5-(dimethylphenylsilyl)pyrazole 
• 263914-87-0 (R)-4-(dimethyl(phenyl)silyl)-but-3-yn-2-ol 
• 142697-17-4 (S)-4-(dimethyl(phenyl)silyl)-but-3-yn-2-ol 

Relevant articles and documents

Ru-Catalyzed Migratory Geminal Semihydrogenation of Internal Alkynes to Terminal Olefins

Semihydrogenation of alkynes to alkenes represents a fundamentally useful transformation. In addition to the well-known cis- and trans-semihydrogenation, herein a geminal semihydrogenation of internal alkynes featuring 1,2-migration is described, which pr

Enantioselective synthesis of both enantiomers of various propargylic alcohols by use of two oxidoreductases

The oxidoreductases Lactobacillus brevis alcohol dehydrogenase (LBADH) and Candida parapsilosis carbonyl reductase (CPCR) are suitable catalysts for the reduction of ketones to afford enantiopure sec. alcohols. A broad variety of alkynones (1, 3, and 5) are accepted as substrates and the corresponding propargylic alcohols (2, 4, and 6) are obtained in good yield and excellent enantiomeric excess. By changing the steric demand of the substituents the ee values can be adjusted and even the configurations of the products can be altered.