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1H-1,4-Benzodiazepine is a heterocyclic compound with a seven-membered ring structure, known for its pharmacological significance, particularly in medicinal chemistry. It serves as a core structure for developing compounds with potential therapeutic applications, such as Cholecystokinin (CCK-A) receptor agonists for obesity treatment and central nervous system agents. While structurally related derivatives have been explored for anti-HIV activity, the intact tricyclic framework appears crucial for efficacy. The versatility of 1,4-benzodiazepines is highlighted by their synthetic adaptability, enabling the development of novel derivatives with diverse biological activities.

264-64-2

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264-64-2 Usage

Chemical structure

A benzene ring fused to a seven-membered diazepine ring.

Pharmacological activities

Sedative, anxiolytic, hypnotic, and muscle relaxant effects.

Common uses

Treatment of anxiety, insomnia, and other related conditions.

Mechanism of action

Enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain.

Reduction in nerve cell activity

Calming effect on the central nervous system.

Well-known drugs

Diazepam, alprazolam, and lorazepam.

Risks

Dependence, tolerance, and withdrawal symptoms if used improperly.

Check Digit Verification of cas no

The CAS Registry Mumber 264-64-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 264-64:
(5*2)+(4*6)+(3*4)+(2*6)+(1*4)=62
62 % 10 = 2
So 264-64-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2/c1-2-4-9-8(3-1)7-10-5-6-11-9/h1-7,11H

264-64-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,4-benzodiazepine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:264-64-2 SDS

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