264131-63-7

Basic information

• Product Name: 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenoxy}-malonic acid di-tert-butyl ester
• Synonyms: 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenoxy}-malonic acid di-tert-butyl ester
• CAS NO: 264131-63-7
• Molecular Weight: 1024.22
• Mol File: 264131-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenoxy}-malonic acid di-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenoxy}-malonic acid di-tert-butyl ester(264131-63-7)
• EPA Substance Registry System: 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenoxy}-malonic acid di-tert-butyl ester(264131-63-7)

Safety Data

• Hazardous Substances Data: 264131-63-7(Hazardous Substances Data)

Upstream product

• 168135-77-1 N^α-Fmoc-O'-(O'',O''-di-tert-butyl-2-malonyl)tyrosine 
• 220193-52-2 (2S)-2-amino-N₁-[3-(1-naphthalenyl)propyl]butanediamide 

Downstream Products

• 264131-66-0 2-[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-malonic acid di-tert-butyl ester 
• 264131-67-1 2-[4-(2-(tert-butoxyoxalyl-amino)-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-malonic acid di-tert-butyl ester 
• 264131-65-9 2-[4-((S)-2-Amino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-malonic acid di-tert-butyl ester 

Relevant articles and documents

Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic

Nonhydrolyzable phosphotyrosyl (pTyr) mimetics serve as important components of many competitive Grb2 SH2 domain inhibitors. To date, the most potent of these inhibitors have relied on phosphonate-based structures to replace the 4-phosphoryl group of the