264131-69-3

Upstream product

• 264131-68-2 2-{4-[2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenyl}-malonic acid di-tert-butyl ester 
• 220193-52-2 (2S)-2-amino-N₁-[3-(1-naphthalenyl)propyl]butanediamide 
• 261513-67-1 N^α-Fmoc-4-(di-tert-butoxycarbonyl-methyl)-L-phenylalanine 

Downstream Products

• 264131-71-7 2-[4-(2-(tert-butoxyoxalyl-amino)-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-malonic acid di-tert-butyl ester 
• 264131-70-6 2-[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-malonic acid di-tert-butyl ester 

Relevant academic research and scientific papers

Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic

Nonhydrolyzable phosphotyrosyl (pTyr) mimetics serve as important components of many competitive Grb2 SH2 domain inhibitors. To date, the most potent of these inhibitors have relied on phosphonate-based structures to replace the 4-phosphoryl group of the