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Thymidine,5'-O-phosphonothymidylyl-(3'→5')- is a complex organic compound that plays a significant role in molecular biology. It is a derivative of thymidine, a nucleoside composed of the base thymine attached to a ribose sugar. The compound in question features a phosphonate group attached to the 5' position of the ribose, and an additional thymidine molecule linked through a phosphodiester bond between the 3' carbon of the first thymidine and the 5' carbon of the second thymidine. This structure is of interest in the study of DNA and RNA, as it mimics the natural phosphodiester linkages found in these nucleic acids but with a stable phosphonate bond, which can be used to investigate the properties and interactions of nucleic acids in biological systems.

2642-45-7

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2642-45-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2642-45-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,4 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2642-45:
(6*2)+(5*6)+(4*4)+(3*2)+(2*4)+(1*5)=77
77 % 10 = 7
So 2642-45-7 is a valid CAS Registry Number.

2642-45-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl [(2R,3S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate

1.2 Other means of identification

Product number -
Other names Dithymidylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2642-45-7 SDS

2642-45-7Upstream product

2642-45-7Relevant academic research and scientific papers

PROTECTION OF 5'-TERMINAL PHOSPHATE OF DEOXYRIBOOLIGONUCLEOTIDES BY USE OF o,o'-DIAMINOBIPHENYL

Nishizawa, Makoto,Kurihara, Takashi,Hata, Tsujiaki

, p. 175 - 178 (2007/10/02)

Cyclic phosphorodianilidate derivatives of nucleoside 5'-phosphates were prepared by use of triphenylphosphine and 2,2'-dipyridyl disulfide as condensing agent and used for the synthesis of oligodeoxyribonucleotides.Removal of the diamino group was remarkably accelerated by coaddition of AgOAc and acid anhydrides to the conventional system, iAmONO-pyridine-AcOH.

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