264204-41-3

Basic information

• Product Name: 7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester
• CAS NO: 264204-41-3
• Molecular Weight: 402.488
• Mol File: 264204-41-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester(264204-41-3)
• EPA Substance Registry System: 7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester(264204-41-3)

Safety Data

• Hazardous Substances Data: 264204-41-3(Hazardous Substances Data)

Upstream product

• 149862-37-3 (R)-3-<(tert-butyldimethylsilyl)oxy>-4-phenoxy-1-butyne 
• 117254-07-6 (4R)-2-(N,N-diethylamino)methyl-4-(t-butyldimethylsiloxy)-cyclopent-2-en-1-ol 
• 14273-91-7 methyl 6-iodohexanoate 
• 264204-39-9 16-phenoxy-17,18,19,20-tetranor-13,14-didehydro-PGE₁ methyl ester 11,15-bis(t-butyldimethylsilyl ether) 

Relevant articles and documents

Synthesis and structure-activity relationships of a new class of selective EP3 receptor agonist, 13,14-didehydro-16-phenoxy analogues of prostaglandin E1

A series of 13,14-didehydro-16-phenoxy analogues of prostaglandin E1 was synthesized and their agonistic activity on EP receptor subtypes was evaluated. 13,14-Didehydro-16-phenoxy-1-decarboxy analogues, 7e and 7f, display highly selective activity on the EP3 receptor subtype, thus, their utility as a selective anti-ulcer agent can be expected. (C) 2000 Elsevier Science Ltd.