264208-61-9Relevant academic research and scientific papers
Magnesium Chloride-Promoted Michael Addition of Dimethylsilyl Enolates to α-Enones
Miura, Katsukiyo,Nakagawa, Takahiro,Hosomi, Akira
, p. 2068 - 2070 (2007/10/03)
In the presence of MgCl2, dimethylsilyl (DMS) enolates 1 smoothly reacted with α-enones in DMF to form 1,5-diketones 3 in moderate to high yields. The Michael addition proceeded with moderate to high anti-diastereoselectivity.
A continuous Michael and aldol coupling of α,β-enones catalyzed by iridium complexes
Matsuda, Isamu,Makino, Tatsuya,Hasegawa, Yuki,Itoh, Kenji
, p. 1409 - 1412 (2007/10/03)
Ir[(COD)(PPh3)2]OTf activated by H2 molecule catalyzes Michael-type coupling of α,β-enones with enoxysilanes to give 1,5-dicarbonyl compounds after the subsequent protodesilylation. An identical catalyst system makes it possible to attain a continuous Michael and aldol modification toward α,β- enones in a one-pot operation. (C) 2000 Elsevier Science Ltd.
