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(17alpha)-pregn-4-ene-3,11,20-trione, also known as 17alpha-hydroxyprogesterone, is a steroid hormone and a derivative of progesterone. It plays a crucial role in the female reproductive system during pregnancy and is involved in the regulation of the menstrual cycle and the maintenance of pregnancy. This chemical compound is significant in the field of endocrinology and pharmaceuticals due to its important physiological functions.

26423-78-9

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26423-78-9 Usage

Uses

Used in Pharmaceutical Industry:
(17alpha)-pregn-4-ene-3,11,20-trione is used as a key ingredient in the production of various medications for its hormonal properties. It is utilized in the development of hormonal contraceptives to prevent pregnancy by inhibiting ovulation, altering the cervical mucus, and changing the lining of the uterus. Additionally, it is used in hormone replacement therapy for menopausal women to alleviate symptoms associated with the hormonal changes during menopause, such as hot flashes and vaginal dryness.
Used in Endocrinology Research:
In the field of endocrinology, (17alpha)-pregn-4-ene-3,11,20-trione is used as a research compound to study the effects of progesterone and its role in the female reproductive system. It aids in understanding the complex interactions between hormones and their impact on fertility, pregnancy, and overall reproductive health. This knowledge is essential for developing new treatments and therapies for various reproductive disorders and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 26423-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,4,2 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 26423-78:
(7*2)+(6*6)+(5*4)+(4*2)+(3*3)+(2*7)+(1*8)=109
109 % 10 = 9
So 26423-78-9 is a valid CAS Registry Number.

26423-78-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione

1.2 Other means of identification

Product number -
Other names 4-Pregnen-3,11,20-trion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:26423-78-9 SDS

26423-78-9Downstream Products

26423-78-9Relevant academic research and scientific papers

New steroid 11-ketone group oxidation synthesizing process

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Paragraph 0130; 0131; 0132, (2016/10/09)

The invention discloses a new steroid 11-ketone group oxidation synthesizing process. The method comprises that in a nonprotic organic solvent, under conditions of dimethyl sulfoxide (DMSO) as an oxidant, an organic alkali, dichlorophenyl phosphate and a piperidine aminoxyl free radical, a steroid 11-alpha hydroxyl compound is subjected to an oxidation reaction to generate a steroid 11-ketone group compound, the reaction temperature is -10 DEG C to a solvent reflux temperature, and the piperidine aminoxyl free radical is selected from the group consisting of a 2,2,6,6-tetramethylpiperidine-1-oxyl free radical or an analogue thereof.

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