26424-07-7

Usage

Uses

Used in Pharmaceutical Research and Development:
3-(3-METHOXY-PHENYLAMINO)-PROPIONITRILE is used as a starting material for the synthesis of various pharmaceutical products. Its unique structure and properties make it a valuable component in the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
3-(3-METHOXY-PHENYLAMINO)-PROPIONITRILE is used as a versatile building block in organic synthesis, allowing for the creation of a wide range of chemical compounds and molecules. Its reactivity and solubility in organic solvents contribute to its utility in this field.
Used in Agrochemical Product Synthesis:
3-(3-METHOXY-PHENYLAMINO)-PROPIONITRILE is also used as a starting material in the synthesis of various agrochemical products, such as pesticides and herbicides. Its properties make it suitable for the development of effective and environmentally friendly agrochemicals.
Used in Research Applications:
3-(3-METHOXY-PHENYLAMINO)-PROPIONITRILE is being investigated for its potential pharmacological activity and biological effects in various research applications. Its unique structure and properties make it a promising candidate for further exploration in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C10H12N2O/c1-13-10-5-2-4-9(8-10)12-7-3-6-11/h2,4-5,8,12H,3,7H2,1H3

Upstream product

• 536-90-3 m-Anisidine 
• 107-13-1 acrylonitrile 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of 3-[(4-Oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile derivatives as orally active AMPA receptor antagonists

In our search for novel orally active α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, we found that conversion of an allyl group in the lead compound 2-[allyl(4-methyl-phenyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one (4)

Synthesis, Characterization and Catalytic Application of MCM 41 Supported Phenanthrolinium Dibromide Catalyst for Aza-Michael Addition Reaction in Aqueous Medium

Abstract: MCM-41 immobilized phenanthrolinium dibromide (phen-MCM-Br2) was easily prepared and applied as an efficient heterogeneous catalyst for aza-Michael addition of aromatic amines to α,β-unsaturated nitriles and nitro compounds in water. The catalyst was characterized by CHN, TGA, FT-IR, SEM, EDAX, XRD, BET, and TEM. It could be simply recovered and reused several times without significant loss of catalytic activity. Graphical Abstract: [Figure not available: see fulltext.]

Boric acid/glycerol as an efficient catalyst for synthesis of thiomorpholine 1,1-dioxide by double michael addition reaction in water

Thiomorpholine 1,1-dioxides were prepared with double Michael addition reaction of aromatic amines to divinyl sulfone catalyzed by boric acid/glycerol in water. This catalyst system was also used for the Michael addition reaction of aromatic amines to electron-deficient alkenes. The reaction is simple and green and gives good to excellent yields.

Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating

The use of two silicon carbide plates is reported for the preparation of three libraries of organic molecules using microwave heating. In addition, a preliminary study has been carried out, showing that one of the plates can also be used in a proteomics setting. Both the 24-position and 48-position plates heated evenly when irradiated with microwave energy. The 48-position plate was used to prepare a library of N-aryl functionalized β-amino esters via an aza-Michael reaction between anilines and Michael acceptors. The 24-position plate was used to prepare a library of biaryls via a Suzuki coupling methodology and a library of 1,4-dihydropyridines via a Hantzsch synthesis. The 48-position plate was also used to perform the proteolytic digestion of insulin chain B by trypsin. The Royal Society of Chemistry 2009.