264255-80-3

Basic information

• Product Name: 5-Allyl-1-(4-tolylsulfonyl)pyrrolidin-2-one
• Synonyms: 5-Allyl-1-(4-tolylsulfonyl)pyrrolidin-2-one
• CAS NO: 264255-80-3
• Molecular Weight: 279.36
• Mol File: 264255-80-3.mol

Chemical Properties

• CAS DataBase Reference: 5-Allyl-1-(4-tolylsulfonyl)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Allyl-1-(4-tolylsulfonyl)pyrrolidin-2-one(264255-80-3)
• EPA Substance Registry System: 5-Allyl-1-(4-tolylsulfonyl)pyrrolidin-2-one(264255-80-3)

Safety Data

• Hazardous Substances Data: 264255-80-3(Hazardous Substances Data)

Upstream product

• 82259-09-4 (racemic)-5-(2'-propenyl)-2-pyrrolidinone 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 264255-81-4 Trifluoromethanesulfonic acid 5-allyl-1-(4-tolylsulfonyl)-4,5-dihydro-1H-pyrrol-2-yl ester 
• 264255-85-8 2-Allyl-5-phenylsulfonylmethyl-1-(4-tolylsulfonyl)-2,3-dihydro-1H-pyrrole 
• 264255-82-5 5-Allyl-1-(4-tolylsulfonyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 264255-83-6 [5-Allyl-1-(4-tolylsulfonyl)-4,5-dihydro-1H-pyrrol-2-yl]methanol 
• 264255-84-7 2-Allyl-5-iodomethyl-1-(4-tolylsulfonyl)-2,3-dihydro-1H-pyrrole 

Relevant articles and documents

Formation of medium-size bridged ring systems via ring-closing metathesis of 2,5-disubstituted-2,3-dihydro-1H-pyrroles

A series of 2,5-disubstituted-2,3-dihydro-1H-pyrroles were prepared via diastereoselective alkylations of sulfone 10. Ring-closing metathesis (RCM), using Grubbs catalyst, provided bridged ring systems with newly formed 9-to 12-membered rings in moderate to good yields. The 9-membered ring was formed as a single Z-isomer whereas the 10- to 12-membered rings were formed as mixtures of E- and Z-isomers. It was shown that the minor diastereomer obtained from the alkylation product 11c failed to undergo RCM, illustrating the crucial aspect of substrate conformation.