264260-38-0

Basic information

• Product Name: N-(3,5-Bis(trifluoroMethyl)benzyl)-2-(tritylaMino)acetaMide
• Synonyms: N-(3,5-Bis(trifluoroMethyl)benzyl)-2-(tritylaMino)acetaMide
• CAS NO: 264260-38-0
• Molecular Formula: C₃₀H₂₄F₆N₂O
• Molecular Weight: 542.5147792
• Mol File: 264260-38-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 581.2±50.0 °C(Predicted)
• Appearance: /
• Density: 1.277±0.06 g/cm3(Predicted)
• PKA: 14.42±0.46(Predicted)
• CAS DataBase Reference: N-(3,5-Bis(trifluoroMethyl)benzyl)-2-(tritylaMino)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,5-Bis(trifluoroMethyl)benzyl)-2-(tritylaMino)acetaMide(264260-38-0)
• EPA Substance Registry System: N-(3,5-Bis(trifluoroMethyl)benzyl)-2-(tritylaMino)acetaMide(264260-38-0)

Safety Data

• Hazardous Substances Data: 264260-38-0(Hazardous Substances Data)

Upstream product

• 5893-05-0 Trt-Gly 
• 85068-29-7 3,5-bis-trifluoromethylbenzylamine 

Downstream Products

• 264260-33-5 N-{[(3,5-bis-trifluoromethyl-benzyl)-methyl-carbamoyl]-methyl}-2,4-dihydroxy-butyramide 
• 264260-35-7 N-(3,5-bis-trifluoromethyl-benzyl)-N-methyl-2-(3-phenyl-butylamino)-acetamide 
• 264260-36-8 N-{[(3,5-bis-trifluoromethyl-benzyl)-methyl-carbamoyl]-methyl}-2-hydroxy-acetamide 
• 264260-34-6 N-(3,5-bis-trifluoromethyl-benzyl)-2-(2-hydroxy-1-methyl-propylamino)-N-methyl-acetamide 
• 264260-39-1 2-tritylamino-N-[3,5-bis(trifluoromethyl)benzyl]-N-methylacetamide 
• 279682-93-8 2-amino-N-(3,5-bis(trifluoromethyl)benzyl)acetamide 

Relevant articles and documents

AMACE1: Versatile aminoacetamide electrophore reagent

Acetamide, 2-amino-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-, monohydrochloride, which we have named AMACE1, was synthesized in three steps starting from N-tritylglycine. AMACE1 was coupled via its primary amine group (pK(a) 8.2) under aqueous conditions to four model analytes for oxidative sugar damage to DNA: glycolate, 3-hydroxy-2-butanone, 3-phenylbutyraldehyde, and α-hydroxy-γ-butyrolactone, relying on cyanoborohydride for coupling to a keto function and a water-soluble carbodiimide for coupling to a carboxyl function. Further reaction with butyric anhydride led to products that could be detected by gas chromatography/electron capture mass spectrometry when 1 μL of ethyl acetate containing essentially 20 amol of each product was injected, on the basis of selected ion monitoring of the analyte characteristic anion fragment from dissociative loss of the 3,5- bis(trifluoromethyl)phenylmethyl moiety: m/z 215, 289, 299, and 329, respectively. Since many small, organic analytes contain a keto or carboxylic acid group, AMACE1 should be useful in general in the area of trace organic analysis.