264279-20-1

Basic information

• Product Name: 1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile
• Synonyms: 1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile
• CAS NO: 264279-20-1
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.2322
• Mol File: 264279-20-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 249.2±23.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform, Dichloromethane, Diethyl Ether, Ethyl Acetate
• CAS DataBase Reference: 1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile(264279-20-1)
• EPA Substance Registry System: 1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile(264279-20-1)

Safety Data

• Hazardous Substances Data: 264279-20-1(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Oil

Uses

1,3,3-TriMethyl-7-oxabicyclo[4.1.0]heptane-2-carbonitrile is used in the synthesis of Retinoic acid derivatives.

Upstream product

• 5585-39-7 (E)-3,7-dimethylocta-2,6-dienenitrile 
• 5146-66-7 geranonitrile 
• 110-93-0 6-Methyl-hept-5-en-2-on 
• 57524-13-7 2,6,6-trimethyl-2-cyclohexenecarbonitrile 
• 23089-87-4 5-methyl-4-hexenenitrile 

Downstream Products

• 6890-91-1 (3RS,all-E)-hydroxyretinal 
• 7584-74-9 C₂₀H₂₈O₂ 
• 80736-89-6 (2E,4E)-1-bromo-3-methyl-5-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4-pentadiene 
• 94669-81-5 (E)-6-Hydroxy-3-(5-hydroxy-3-methyl-1,3-pentadienyl)-2,4,4-trimethyl-2-cyclohexen-1-on 
• 56830-39-8 2,4,4-Trimethylcyclohex-2-en-1-one-3-carbonitrile 
• 29538-78-1 (2E,4E)-3-methyl-5-(2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4-pentadienol 
• 7542-45-2 3,3'-dihydroxy-β,β-carotene-4,4'-dione 
• 60078-92-4 2,4,4-trimethyl-3-formyl-2-cyclohexen-1-ol 
• 42926-75-0 2,6,6-trimethyl-4-hydroxy-1-cyclohexene-1-carboxaldehyde 

Relevant articles and documents

COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS

A method of treating an ocular disorder in a subject associated with increased all-trans-retinal in an ocular tissue includes administering to the subject a therapeutically effective amount of a primary amine compound of formula (I); and pharmaceutically acceptable salts thereof.

Synthetic scheme for the preparation of 13C-labeled 3,4-didehydro-retinal, 3-hydroxyretinal, and 4-hydroxyretinal up to uniform 13C-enrichment

A modular synthetic scheme has been developed for the synthesis of 13C-labeled naturally occurring visual pigment chromophores; 3,4-didehydroretinal, 3-hydroxyretinal, and 4-hydroxyretinal. These compounds can now be made with > 99% 13C enrichment at any position or combination of positions. We used the common C10+C5+C5 scheme for the synthesis of retinals, and by making variations in the C10 part we can now prepare the desired retinal derivatives with selective or uniform 13C enrichment. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.