264279-39-2

Upstream product

• 264279-37-0 C₉⁽¹³⁾CH₁₅N 
• 264279-36-9 C₉⁽¹³⁾CH₁₅N 
• 125095-55-8 [2-13C]-5-methyl-4-hexenenitrile 
• 264279-38-1 C₉⁽¹³⁾CH₁₅NO 

Downstream Products

• 264279-40-5 C₉⁽¹³⁾CH₁₃NO 
• 264279-45-0 C₁₄⁽¹³⁾CH₂₂O₂ 
• 264279-46-1 C₁₄⁽¹³⁾CH₂₂O₃ 

Relevant academic research and scientific papers

Synthesis and characterization of all-E-(4,4'-13C2)-astaxanthin strategies for labelling the C15-end groups of carotenoids

The all-E isomer of (4,4'-13C2)astaxanthin (1a) has been prepared by total synthesis starting from commercially available 99% 13C enriched acetonitrile. The labelled astaxanthin was obtained in high purity and with high isotope incorporation. For this synthesis, the C15 + C10 + C15 strategy was used. The central C10-synthon, 2,7-dimethylocta-2,4,6-triene- 1,8-dial (3), was coupled with 13C-enriched C15-phosphonium salt 2a. The new synthetic scheme for the preparation of the C15-phosphonium salt is discussed in this paper; the same scheme can be used to label all positions and combinations of positions of the C15-phosphonium salt.