26458-04-8Relevant articles and documents
Merging visible-light photocatalysis and transition-metal catalysis in the copper-catalyzed trifluoromethylation of boronic acids with CF3I
Ye, Yingda,Sanford, Melanie S.
supporting information; experimental part, p. 9034 - 9037 (2012/07/13)
This communication describes the development of a mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox and Cu catalysis. This method has been applied to the trifluoromethylation of electronically diverse aromatic and heteroaromatic substrates and tolerates many common functional groups.
Copper electron-transfer induced trifluoromethylation with methyl fluorosulphonyldifluoroacetate
Chen, Qing-Yun,Yang, Guo-Ying,Wu Sheng-Wen
, p. 291 - 298 (2007/10/02)
Treatment of halogen compounds, RX, with methyl fluorosulfonyldifluoroacetate and copper powder in dimethylformamide for 4 h at 65 - 80 deg C resulted in the corresponding trifluoromethylated products, RCF3, in good yield.In the absence of halogen compounds and at 100 deg C, methyl triflone (CF3SO2CH3) was synthesized readily in the 20 - 30percent yield from the same reaction system.The fact that the reaction was suppressed by oxygen, p-dinitrobenzene or in the darkness suggested that a copper-induced electron-transfer process was involved in this new trifluoromethylating system.
