26482-00-8Relevant articles and documents
pH-Dependent ion permeability control of a modified amphotericin B channel through metal complexation
Koshiyama, Tomomi,Inoue, Yuki,Asada, Sana,Kawahara, Koki,Ide, Shogo,Yasuhara, Kazuma,Ohba, Masaaki
, p. 2895 - 2898 (2021)
Amphotericin B incorporating 2,2'-bipyridine (bpy-AmB) forms a membrane channel exhibiting pH-dependent Ca2+ion permeability with a selective response to Cu2+ions. The coordination structure at bpy sites depends on the pH and metal ions can control the association state of bpy-AmB in the membrane.
Synthesis, spectral and third-order nonlinear optical properties of terpyridine Zn(II) complexes based on carbazole derivative with polyether group
Kong, Ming,Liu, Yanqiu,Wang, Hui,Luo, Junshan,Li, Dandan,Zhang, Shengyi,Li, Shengli,Wu, Jieying,Tian, Yupeng
, p. 521 - 528 (2015)
Four novel Zn(II) terpyridine complexes (ZnLCl2, ZnLBr 2, ZnLI2, ZnL(SCN)2) based on carbazole derivative group were designed, synthesized and fully characterized. Their photophysical properties including absorp
Multidrug resistance regulators (MDRs) as scaffolds for the design of artificial metalloenzymes
Bersellini, Manuela,Roelfes, Gerard
, p. 3069 - 3073 (2017)
The choice of protein scaffolds is an important element in the design of artificial metalloenzymes. Herein, we introduce Multidrug Resistance Regulators (MDRs) from the TetR family as a viable class of protein scaffolds for artificial metalloenzyme design. In vivo incorporation of the metal binding amino acid (2,2-bipyridin-5yl)alanine (BpyA) by stop codon suppression methods was used to create artificial metalloenzymes from three members of the TetR family of MDRs: QacR, CgmR and RamR. Excellent results were achieved with QacR Y123BpyA in the Cu2+ catalyzed enantioselective vinylogous Friedel-Crafts alkylation reaction with ee's up to 94% of the opposite enantiomer that was achieved with other mutants and the previously reported LmrR-based artificial metalloenzymes.
Photoinduced electron transfer in a triad that can be assembled/disassembled by two different external inputs. Toward molecular-level electrical extension cables
Ballardini, Roberto,Balzani, Vincenzo,Clemente-Leon, Miguel,Credi, Alberto,Teresa Gandolfi, Maria,Ishow, Elena,Perkins, Julie,Fraser Stoddart,Tseng, Hsian-Rong,Wenger, Sabine
, p. 12786 - 12795 (2002)
We have designed, synthesized, and investigated a self-assembling supramolecular system which mimics, at a molecular level, the function performed by a macroscopic electrical extension cable. The system is made up of three components, 12+, 2-H
Role of the X Coligands in Cyclometalated [Ni(Phbpy)X] Complexes (HPhbpy = 6-Phenyl-2,2′-bipyridine)
Chin, Mason T.,H?rner, Gerald,Klein, Axel,Kletsch, Lukas,Sandleben, Aaron,Sch?fer, Sascha,Vicic, David A.,Vogt, Nicolas
supporting information, p. 1776 - 1785 (2021/06/28)
The coligand X was varied in the organonickel complexes [Ni(Phbpy)X] (X = F, Cl, Br, I, C6F5) carrying the anionic tridentate CNN ligand 6-(phen-2-ide)-2,2′-bipyridine (Phbpy-) to study its effect on electronic structures of these complexes and their activity in Negishi-like C-C cross-coupling catalysis. The complexes were synthesized from the precursor [Ni(COD)2] (COD = 1,5-cyclooctadiene) by chelate-assisted oxidative addition into the phenyl C-X bond of the protoligand 6-(2-halidophenyl)-2,2′-bipyridine) and were obtained as red powders. Protoligands X-Phbpy carrying the halide surrogates X = OMe, OTf (triflate) failed in this reaction. Single-crystal XRD allowed us to add the structures of [Ni(Phbpy)Cl] and [Ni(Phbpy)I] to the previously reported Br derivative. Cyclic voltammetry showed reversible reductions for X = C6F5, F, Cl, while for Br and I the reversibility is reduced through rapid splitting of X- after reduction (EC mechanism). UV-vis spectroelectrochemistry confirmed the decreasing degree of reversibility along the series C6F5 > F > Cl ? Br > I, which parallels the "leaving group character"of the X coligands. This method also revealed mainly bpy centered reduction and essentially Ni(II)/Ni(III) oxidations, as corroborated by DFT calculations. The rather X-invariant long-wavelength UV-vis absorptions and excited states were analyzed in detail using TD-DFT and were consistent with predominant metal to ligand charge transfer (MLCT) character. Initial catalytic tests under Negishi-like conditions showed the complexes to be active as catalysts in C-C cross-coupling reactions but did not display marked differences along the series from Ni-F to Ni-I.
Cyclization of Active Methylene Isocyanides with α-Oxodithioesters Induced by Base: An Expedient Synthesis of 4-Methylthio/Ethoxycarbonyl-5-acylthiazoles
Anil, Seegehalli M.,Kiran, Kuppalli R.,Rajeev, Narasimhamurthy,Rangappa, Kanchugarakoppal S.,Sadashiva, Maralinganadoddi P.,Swaroop, Toreshettahally R.
, p. 1444 - 1450 (2020/04/27)
Cyclization of tosylmethyl isocyanide with α-oxodithioesters in the presence of KOH is reported for the synthesis of 4-methylthio-5-acylthiazoles. Similarly, ethyl isocyanoacetate underwent cyclization with α-oxodithioesters to form 4-ethoxycarbonyl-5-acy
