264875-15-2

Upstream product

• 55418-52-5 cassione 
• 264875-14-1 1-Methoxy-(1-phenylsulfanyl)-2-methyl-4-(3,4-methylenedioxyphenyl)butan-2-ol 

Downstream Products

• 120749-41-9 (2RS,3RS,4RS)-2,4-Dimethyl-6-(3,4-methylenedioxyphenyl)-4-phenylsulfanylhexane-1,3-diol 
• 120749-41-9 (2RS,3RS,4SR)-2,4-Dimethyl-6-(3,4-methylenedioxyphenyl)-4-phenylsulfanylhexane-1,3-diol 
• 120749-42-0 (2SR,3RS,4SR)-2,4-Dimethyl-2-[2-(3,4-methylenedioxyphenyl)ethyl]-3-phenylsulfanyltetrahydrofuran 
• 120749-42-0 (2RS,3RS,4SR)-2,4-Dimethyl-2-[2-(3,4-methylenedioxyphenyl)ethyl]-3-phenylsulfanyltetrahydrofuran 

Relevant academic research and scientific papers

Stereochemical control in the synthesis of tetrahydrofurans by cyclisation of diols with [1,2]phenylsulfanyl migration

Acid catalysed rearrangement of a series of 4-PhS-1,3-diols with toluene-p-sulfonic acid in benzene gives stereospecifically substituted 3-PhS-tetrahydrofurans in excellent yield via a [1,2]-SPh shift. We comment on the structural variation at both the migration origin and terminus on the outcome of the title reaction and define its limits.