264882-11-3

Basic information

• Product Name: methyl (R)-α-cyclohexyl-3-bromophenylacetate
• Synonyms: methyl (R)-α-cyclohexyl-3-bromophenylacetate
• CAS NO: 264882-11-3
• Molecular Weight: 311.219
• Mol File: 264882-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (R)-α-cyclohexyl-3-bromophenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-α-cyclohexyl-3-bromophenylacetate(264882-11-3)
• EPA Substance Registry System: methyl (R)-α-cyclohexyl-3-bromophenylacetate(264882-11-3)

Safety Data

• Hazardous Substances Data: 264882-11-3(Hazardous Substances Data)

Upstream product

• 150529-73-0 methyl 2-(3-bromophenyl)acetatee 
• 110-82-7 cyclohexane 
• 264882-03-3 methyl 2-(3-bromophenyl)-2-diazoacetate 

Relevant articles and documents

Catalytic Asymmetric C-H Activation of Alkanes and Tetrahydrofuran

Rhodium carbenoids derived from methyl aryldiazoacetates are capable of effective catalytic asymmetric C-H activation of a range of alkanes and tetrahydrofuran by a C-H insertion mechanism. Dirhodium tetrakis(S-(N-dodecylbenzenesulfonyl)prolinate) (Rh2(S-DOSP)4) catalyzed decomposition of methyl aryldiazoacetates in the presence of alkanes results in intermolecular C-H insertions with good control of regioselectivity, diastereoselectivity, and enantioselectivity. The carbenoids derived from methyl aryldiazoacetates are considerably more chemoselective than carbenoids derived from diazoacetates. They strongly favor C-H insertions into secondary and tertiary sites. Formation of side products due to carbene dimerization is not a major problem with rhodium carbenoids derived from aryldiazoacetates.