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(R)-1-Boc-3-pyrrolidineacetic acid, also known as (R)-Boc-β-proline or (R)-pipecolinic acid, is a versatile compound featuring a pyrrolidine ring and a carboxylic acid functional group. It is widely recognized for its applications in the pharmaceutical and agrochemical industries, where it serves as a crucial building block in the synthesis of various drugs and chemicals. Its unique structure and properties make it an essential component in the development of peptide-based drugs and as a chiral auxiliary in asymmetric synthesis, contributing significantly to medicinal chemistry and drug discovery.

264903-86-8

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264903-86-8 Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-Boc-3-pyrrolidineacetic acid is used as a building block for the synthesis of various pharmaceuticals, including peptide-based drugs. Its pyrrolidine ring and carboxylic acid functional group provide a stable and versatile framework for the development of new therapeutic agents, targeting a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-1-Boc-3-pyrrolidineacetic acid is utilized as a key component in the synthesis of various agrochemicals. Its unique structure allows for the creation of compounds with specific biological activities, such as pesticides, herbicides, and fungicides, which are essential for maintaining agricultural productivity and crop protection.
Used in Asymmetric Synthesis:
(R)-1-Boc-3-pyrrolidineacetic acid is employed as a chiral auxiliary in asymmetric synthesis, a crucial technique in the development of enantiomerically pure compounds. Its presence can significantly influence the stereochemistry of the reaction, leading to the formation of desired enantiomers with high selectivity and yield, which is particularly important in the synthesis of pharmaceuticals and other chiral molecules.
Used in Medicinal Chemistry and Drug Discovery:
(R)-1-Boc-3-pyrrolidineacetic acid plays a vital role in medicinal chemistry and drug discovery due to its ability to be incorporated into a wide range of biologically active molecules. Its unique structural features and functional groups make it an attractive candidate for the design and synthesis of novel drug candidates, potentially leading to the development of new treatments for various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 264903-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,4,9,0 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 264903-86:
(8*2)+(7*6)+(6*4)+(5*9)+(4*0)+(3*3)+(2*8)+(1*6)=158
158 % 10 = 8
So 264903-86-8 is a valid CAS Registry Number.

264903-86-8Downstream Products

264903-86-8Relevant articles and documents

Chiral bicyclic guanidine as a versatile bronsted base catalyst for the enantioselective michael reactions of dithiomalonates and β-keto thioesters

Ye, Weiping,Jiang, Zhiyong,Zhao, Yujun,Goh, Serena Li Min,Leow, Dasheng,Soh, Ying-Teck,Tan, Choon-Hong

, p. 2454 - 2458 (2008/09/19)

A chiral bicyclic guanidine was developed as a versatile Bronsted base catalyst for the enantioselective Michael reactions of dithiomalonates and β-keto thioesters using a range of acceptors including maleimides, cyclic enones, furanone and acyclic 1,4-di

Conformationally constrained no synthase inhibitors: Rigid analogs of L- N-iminoethylornithine

Eustache, Jacques,Grob, Alfred,Lam, Charles,Sellier, Odile,Schulz, Gerhard

, p. 2961 - 2966 (2007/10/03)

The synthesis of eight rigid analogs of L-N-iminoethylomithine (L-NIO) is described. The compounds have been evaluated for their inhibition of inducible nitric oxide synthase. Preliminary structure-activity relationships are discussed.

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