264913-44-2Relevant academic research and scientific papers
The synthesis and conformational aspects of a novel dioxopiperazine - A possible β-turn constraint
Davies, John S.,Stelmach-Diddams, Malgosia,Fromentin, Regis,Howells, Alun,Cotton, Ron
, p. 239 - 243 (2000)
The synthesis and conformational aspects of a dioxopiperazine was discussed. The cis configuration of the dioxopiperazine was rationalized using nuclear magnetic resonance (NMR) spectroscopy. Computational energy calculations were performed to explain the reluctance to cyclise of N-terminal partially protected dipeptides containing α, α-amino groups.
