2650-44-4 Usage
Uses
Used in Biochemical Research:
1-NAPHTHYL PHOSPHATE MONOSODIUM SALT MONOHYDRATE is used as a colorimetric substrate for the detection of alkaline phosphatase activity, as it produces a yellow product upon hydrolysis by the enzyme. This makes it an important reagent in the field of biochemistry for the detection and quantification of alkaline phosphatase activity.
Used in Enzyme-Linked Immunosorbent Assays (ELISA):
In the ELISA technique, 1-NAPHTHYL PHOSPHATE MONOSODIUM SALT MONOHYDRATE is used as a substrate to measure the activity of alkaline phosphatase, which is often conjugated to antibodies or other biomolecules of interest. The resulting color change allows for the quantification of the target analyte in the assay.
Used in Diagnostic Applications:
1-NAPHTHYL PHOSPHATE MONOSODIUM SALT MONOHYDRATE is utilized in diagnostic assays to detect and quantify alkaline phosphatase levels, which can be indicative of certain diseases or conditions. Its use in these applications aids in the accurate diagnosis and monitoring of various health-related issues.
Used in Pharmaceutical Development:
1-NAPHTHYL PHOSPHATE MONOSODIUM SALT MONOHYDRATE may also be employed in the development of pharmaceuticals, particularly in assays designed to screen for inhibitors or activators of alkaline phosphatase, which can be relevant for the treatment of certain diseases where the enzyme's activity is implicated.
Check Digit Verification of cas no
The CAS Registry Mumber 2650-44-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,5 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2650-44:
(6*2)+(5*6)+(4*5)+(3*0)+(2*4)+(1*4)=74
74 % 10 = 4
So 2650-44-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H9O4P.Na/c11-15(12,13)14-10-7-3-5-8-4-1-2-6-9(8)10;/h1-7H,(H2,11,12,13);/q;+1/p-1
2650-44-4Relevant academic research and scientific papers
Enzyme synthesis of 1-naphthyl phosphate in aqueous-organic systems
Rutsova, E. A.,Poltorak, O. M.,Chukhrai, E. S.
, p. 1688 - 1690 (2007/10/02)
The reaction of α-naphthol with monosubstituted sodium orthophosphate in the presence of alkaline phosphatase has been studied in the ethyl benzoate-water and diethyl oxalate-water systems.We show that in these systems α-naphthol is phosphorylated at pH 7