2650-74-0Relevant academic research and scientific papers
AMINO ACID DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS
-
Page/Page column 59-60, (2021/10/22)
The present invention provides derivatives of glutamine of formula (I) and derivatives of arginine of formula (II), and the use of such compounds as flavor modifiers. The invention further provides the use of such derivatives of glutamine and arginine to enhance the salty and umami taste of ingestible compositions as ingestible compositions that include such derivatives of glutamine and arginine and bulking agents.
A novel catalytic ability of γ-glutamylcysteine synthetase of Escherichia coli and its application in theanine production
Miyake, Koichiro,Kakita, Shingo
experimental part, p. 2677 - 2683 (2010/09/11)
γ-Glutamylcysteine synthetase (γGCS, EC 6.3.2.2) catalyzes the formation of γ-glutamylcysteine from L-glutamic acid (Glu) and L-cysteine (Cys) in an ATP-dependent manner. While γGCS can use various amino acids as substrate, little is known about whether it can use non-amino acid compounds in place of Cys. We determined that γGCS from Escherichia coli has the ability to combine Glu and amines to form γ-glutamylamides. The reaction rate depended on the length of the methylene chain of the amines in the following order: n-propylamine > butylamine > ethylamine methylamine. The optimal pH for the reaction was narrower and more alkaline than for the reaction with an amino acid. The newly found catalytic ability of γGCS was used in the production of theanine (γ-glutamylethylamine). The resting cells of E. coli expressing γGCS, in which ATP was regenerated through glycolysis, synthesized 12.1 mm theanine (18 h) from 429 mm ethylamine.
NEW CARDENOLIDE GLYCOSIDES FROM THE DEFENCE GLANDS OF CHRYSOLININA BEETLES (COLEOPTERA : CHRYSOMELIDAE)
Oycke, S. Van,Randoux, T.,Braekman, J. C.,Daloze, D.,Pasteels, J. M.
, p. 297 - 312 (2007/10/02)
The composition of the defence secretions of six species of chrysomelid beetles (Chrysolina polita, C. americana, C. grossa, C. herbacea, C. fastuosa, and Oreina gloriosa) belonging to the sub-tribe Chrysolinina has been investigated.Two known cardenolide
