265107-25-3

Usage

Uses

Used in Pharmaceutical Applications:
1-(4-(pyrimidin-5-yl)phenyl)ethan-1-one is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structure and properties. It plays a crucial role in the development of new drugs and materials, contributing to the advancement of the pharmaceutical industry.
Used in Research Applications:
In the field of research, 1-(4-(pyrimidin-5-yl)phenyl)ethan-1-one is employed as a key component in the synthesis of diverse compounds. Its distinctive attributes make it an invaluable resource for scientists and researchers working on the development of novel drugs and materials.
Used in Organic Electronics:
1-(4-(pyrimidin-5-yl)phenyl)ethan-1-one may have potential applications in the field of organic electronics, where its unique structure and properties can be harnessed to create innovative electronic devices and components.
Used as a Precursor for Bioactive Compounds:
This chemical compound also serves as a precursor for the synthesis of bioactive compounds, which can be utilized in various industries, including pharmaceuticals and biotechnology, to develop new and effective treatments for various diseases and conditions.

Upstream product

• 4595-60-2 2-bromopyrimidine 
• 149104-90-5 4-acetylphenylboronic acid 
• 31462-58-5 5-iodopyrimidine 

Relevant academic research and scientific papers

A general Suzuki cross-coupling reaction of heteroaromatics catalyzed by nanopalladium on amino-functionalized siliceous mesocellular foam

Suzuki-Miyaura cross-coupling reactions of heteroaromatics catalyzed by palladium supported in the cavities of amino-functionalized siliceous mesocellular foam are presented. The nanopalladium catalyst effectively couples not only heteroaryl halides with

Synthesis of amido-N-imidazolium salts and their applications as ligands in suzuki-miyaura reactions: Coupling of hetero- aromatic halides and the synthesis of milrinone and irbesartan

A new catalytic system based on palladium-amido-N-heterocyclic carbenes for Suzuki-Miyaura coupling reactions of heteroaryl bromides is described. A variety of sterically bulky, amido-N-imidazolium salts were synthesized in high yields from the corresponding anilines. This catalytic system effectively promoted Suzuki-Miyaura couplings of heteroaryl bromides and chlorides with a range of boronic acids to give the corresponding aryl compounds in high yield. The yield was increased with increasing steric bulkiness of the substituted group. Especially, 1-(2,6-diisopropylphenyl)-3-N-(2,4,6-tri-tert- butylphenylacetamido)imidazolium bromide (4bc) exhibited 850,000 TON in the coupling reaction of 2-bromopyridine and phenylboronic acid. In addition, pharmaceutical compounds such as milrinone and irbesartan were synthesized via Suzuki-Miyaura coupling using sterically bulky, amido-N-imidazolium salt (4bc) as a ligand. Copyright

Nitrogenous tetrahydropyridyl-alkyl-heterocycles with tnf activity

This invention relates to nitrogenous (tetrahydropyridyl)(alkyl)heterocycles, to pharmaceutical compositions comprising them, to processes for preparing them and to the method of use thereof in the treatment of pain and diseases related to immune and inflammatory disorders.