26513-20-2

Usage

Uses

Used in Dye and Pigment Production:
3-(N,N-Dimethylamino)aniline is used as a key intermediate in the synthesis of dyes and pigments for various applications. Its chemical structure allows for the creation of a wide range of colors, making it a versatile component in the production of colorants for textiles, plastics, and printing inks.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 3-(N,N-Dimethylamino)aniline serves as an intermediate in the synthesis of various medicinal compounds. Its unique chemical properties contribute to the development of drugs with specific therapeutic effects, enhancing the range of treatments available for different medical conditions.
Used as a Catalyst in Chemical Reactions:
3-(N,N-Dimethylamino)aniline is also utilized as a catalyst in certain chemical reactions. Its ability to facilitate specific transformations makes it an important component in the production of various organic compounds, contributing to the efficiency and selectivity of these processes.
Used in Organic Compound Synthesis:
As an intermediate in the synthesis of organic compounds, 3-(N,N-Dimethylamino)aniline plays a crucial role in the creation of a diverse array of chemical products. Its involvement in these syntheses is essential for the development of new materials and substances with specific applications in various industries.

InChI:InChI=1/C10H12N2O2/c1-8(13)12-11-7-9-5-3-4-6-10(9)14-2/h3-7H,1-2H3,(H,12,13)

Upstream product

• 6375-46-8 m-acetylamino-N,N-diethylanilne 
• 99-09-2 3-nitro-aniline 
• 91-66-7 N,N-diethylaniline 
• 2216-16-2 N,N-diethyl-3-nitroaniline 
• 108-37-2 1-bromo-3-chlorobenzene 
• 19372-80-6 2-chloro-N,N-diethylaniline 

Downstream Products

• 76751-20-7 lauric acid-(3-diethylamino-anilide) 
• 20246-81-5 4,4'-dinitrodiphenic acid 
• 52603-47-1 m-diethylaminomethanesulfonanilide 
• 88760-92-3 2-(3-(Diaethylamino)phenylamino)-benzothiazol 
• 139448-22-9 Gossypol bis-m-diethylaminophenylimine 
• 22185-75-7 N,N-diethyl-N'-propionyl-1,3-benzenediamine 
• 33065-03-1 C₁₆H₂₀N₂O₂S 
• 870274-40-1 C₁₅H₁₉N₃O₂S 
• 150491-23-9 N,N-diethyl-N'-acetonyl-m-phenylenediamine 
• 1062073-32-8 C₂₄H₂₄ClN₃O 
• 1613111-24-2 C₂₃H₃₀ClN₇ 

Relevant academic research and scientific papers

Design, synthesis, and photophysical characterization of novel pentacyclic red shifted azine dyes

As part of our continuing efforts to develop second generation photodynamic therapeutic agents [1], we synthesized three pentacyclic azine dyes that were designed with the aid of MNDO calculations to absorb visible light having wavelengths longer than 600

Synthesis of novel reactive disperse silicon-containing dyes and their coloring properties on silicone rubbers

Novel red and purple reactive disperse silicon-containing dyes were designed and synthesized using p-nitroaniline and 6-bromo-2,4-dinitro-aniline as diazonium components, the first condensation product of cyanuric chloride and 3-(N,N-diethyl)amino-aniline

RESIN COMPOSITION, OPTICAL FILTER, IMAGE DISPLAY DEVICE, SOLID-STATE IMAGING ELEMENT, AND COLORANT MIXTURE

Provided are a resin composition including a colorant and a resin, in which the colorant contains two or more squarylium colorants represented by Formula (1) below, at least one of the squarylium colorants is a squarylium colorant having a hydrogen-bonding group, which is represented by Formula (2) below, and a colorant mixture consisting of the two or more squarylium colorants, which is included in the resin composition, has a maximum absorption wavelength in a wavelength range of 400 nm to 700 nm; an optical filter; a liquid crystal display device; a solid-state imaging element; and a colorant mixture.

Inter-alkane amidogen phenolic synthetic method (by machine translation)

Inter-alkane amidogen phenolic synthetic method, its characteristic is: 1st step, between the two alkane amidogen acyl aniline and sulfuric acid aqueous solution mixing and heating to 50 - 110 °C, thermal insulation reaction of aniline [...] sulfuric acid aqueous solution; 2nd step, continue to drip the sodium nitrite aqueous solution, sodium nitrite aqueous solution for dropping temperature of - 10 - 20 °C, drop bi yu 5 - 30 °C insulation, [...] aniline obtained diazonium salt of the sulfuric acid aqueous solution; 3rd step, [...] aniline diazonium salt of the sulfuric acid aqueous solution is directly heated to 45 - 110 °C, thermal insulation, in the hydrolysis reaction of the diazonium salt, cooling after treatment, to obtain the product between two alkane amidogen phenol; three-step required by the reaction of sulfuric acid in the 1st step reaction in the finished disposable adding; a three-step reaction in a finish step by step in the pot. The method of the invention with raw materials are cheap, abundant, synthetic high security of the process, the product yield is high, the three waste less pollution and the like, has high industrial value. (by machine translation)

PARTICLES FOR ELECTROPHORETIC DISPLAYS

This invention relates to polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, electrophoretic displays comprising such particle, and new polymerisable dyes.

DIARYLUREAS AS CB1 ALLOSTERIC MODULATORS

The present invention provides novel diarylurea derivatives (compounds of formula (I)) and their uses. The compounds of the present invention are demonstrated to be allosteric modulators of the CB1 receptor, and therefore useful for the treatment of diseases and conditions mediated by CB1.

Catalyst-Directed Chemoselective Double Amination of Bromo-chloro(hetero)arenes: A Synthetic Route toward Advanced Amino-aniline Intermediates

A chemoselective sequential one-pot coupling protocol was developed for preparing several amino-anilines in high yield as building blocks for active pharmaceutical ingredients (APIs). Site (Cl vs Br on electrophile) and nucleophile (amine vs imine) selectivity is dictated by the catalyst employed. A Pd-crotyl(t-BuXPhos) precatalyst selectively coupled the Ar-Br of the polyhaloarene with benzophenone imine, even in the presence of a secondary amine, while Pd-based RuPhos or (BINAP)Pd(allyl)Cl coupled the Ar-Cl site with secondary amines.

Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRα) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs)

Stem cell factor receptor (c-KIT) and platelet derived growth factor receptor alpha (PDGFRα) kinases play an important role in gastrointestinal stromal tumors (GISTs). Here, we have discovered an c-KIT/PDGFRα dual inhibitor, compound 31, with single-digit nanomolar potency against c-KIT and PDGFRα. Compared to Imatinib (1), 31 showed better antiproliferative efficacy against various TEL-c-KIT/PDGFRα-BaF3 isogenic cells, including three 1-resistant BaF3 cell lines, as well as against GIST-T1 and GIST-882 cell lines. Furthermore, compound 31 showed a good KinomeScan selectivity (468 kinases) (S score (1) = 0.01 at 1 μM concentration), good metabolic stability in liver microsomes, and no hERG inhibitory activity. It was worth noting that 31 inhibited GIST-T1 tumor growth (TGI = 81.5%) and even the BaF3-TEL-cKIT-T670I tumor progression (TGI = 41.9%, 1-resistant GISTs) at a dosage of 100 mg/kg/day without exhibiting apparent toxicity.

COLORED CURABLE RESIN COMPOSITION

The present invention provides a colored curable resin composition comprising: one or more kinds of colorants (A1) selected from the group of C.I. pigment yellow 138, a green pigment and a yellow pigment, Squarylium dye (A2), resin (B), polymer compounds

METAL FREE ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE

The present invention relates to dyes of formula (1) a process for preparing them and their use for dyeing and printing hydroxyl- and/or carboxamido-containing materials.