26530-09-6

Basic information

• Product Name: 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone
• Synonyms: 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone
• CAS NO: 26530-09-6
• Molecular Formula: C₁₀H₈ClNOS
• Molecular Weight: 225.69462
• Mol File: 26530-09-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone(26530-09-6)
• EPA Substance Registry System: 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone(26530-09-6)

Safety Data

• Hazardous Substances Data: 26530-09-6(Hazardous Substances Data)

Usage

General Description

2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone is a chemical compound that belongs to the class of isothiazolone derivatives. It is commonly used as a preservative in a variety of personal care and household products, such as shampoos, conditioners, and cleaning agents. 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone has antimicrobial properties and is effective against a broad spectrum of bacteria, fungi, and algae, making it valuable for prolonging the shelf life of products and preventing spoilage. However, it is important to note that it can cause skin and eye irritation in concentrated form, so it should be handled and used with caution. Additionally, there is some concern about its potential for causing allergic reactions in sensitive individuals. Despite these considerations, 2-(4-Chlorophenylmethyl)-3(2H)-isothiazolone is widely used as a biocide in many commercial and industrial applications.

Upstream product

• 33312-09-3 N,N'-bis-(4-chloro-benzyl)-3,3'-disulfanediyl-bis-propionamide 

Downstream Products

• 642087-83-0 N-(4-chlorobenzyl)isothiazol-3-amine 
• 62094-59-1 4,4,5,5-tetrachloro-2-(4-chloro-benzyl)-isothiazolidin-3-one 
• 64359-77-9 4-bromo-2-(4-chloro-benzyl)-isothiazol-3-one 

Relevant articles and documents

Isothiazoles. Part 14: New 3-aminosubstituted isothiazole dioxides and their mono- and dihalogeno derivatives

3-Alkylamino- and 3-arylamino isothiazole dioxides unsubstituted at C-4 and C-5 were synthesized starting from dithiopropionic amides. Taking advantage of the direct chlorination during the cyclization process or realizing an addition-elimination process with bromine on the final 3-aminoisothiazole dioxide derivatives, the corresponding 5-chloro-, 4,5-dichloro- or the 4-bromoisothiazole dioxides could also be made available.