265312-58-1Relevant articles and documents
5-Arylamino-2-methyl-4,7-dioxobenzothiazoles as inhibitors of cyclin-dependent kinase 4 and cytotoxic agents
Ryu, Chung-Kyu,Kang, Hye-Young,Lee, Sang Kook,Nam, Kyung Ae,Hong, Chang Yong,Ko, Won-Gil,Lee, Byung-Hoon
, p. 461 - 464 (2000)
5-Arylamino-2-methyl-4,7-dioxobenzothiazoles were synthesized as inhibitors of cyclin-dependent kinase 4 (CDK4) and cytotoxic agents. Most of the 4,7-dioxobenzothiazoles exhibited selective inhibitory activities for the CDK4 and cytotoxic potential agains
Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C
Lavergne, Olivier,Fernandes, Anne-Cecile,Brehu, Laetitia,Sidhu, Alban,Brezak, Marie-Christine,Prevost, Gregoire,Ducommun, Bernard,Contour-Galcera, Marie-Odile
, p. 171 - 175 (2007/10/03)
A focused set of heterocyclic quinones based on the benzothiazole, benzoxazole, benzimidazole, indazole and isoindole was prepared and screened with respect to the inhibition of the phosphatase activity of CDC25C. Benzoxazole- and benzothiazole-diones wer