26532-06-9

Upstream product

• 125901-90-8 (2R,3S)-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-ol 
• 850753-00-3 4,6-di-O-benzyl-1,5-anhydro-D-erythrohex-2-enitol 
• 149342-25-6 ((2R,3S)-3-acetoxy-3,6-dihydro-2H-pyran-2-yl)methyl acetate 
• 2873-29-2 D-glucal triacetate 
• 5987-34-8 3-O-acetyl-1,5-anhydro-4,6-O-benzylidene-2-deoxy-D-ribo-hex-1-enitol 

Downstream Products

• 110522-33-3 2-chloro-2,3-dideoxy-α-D-arabino-hexopyranosyl chloride 
• 110522-32-2 4-chlorobutyl 2-chloro-2,3-dideoxy-α-D-arabino-hexopyranoside 
• 110522-34-4 4-chlorobutyl 2-chloro-2,3-dideoxy-β-D-ribo-hexopyranoside 

Relevant academic research and scientific papers

1′,5′-Anhydro-L-ribo-hexitol Adenine Nucleic Acids (α-L-HNA-A): Synthesis and Chiral Selection Properties in the Mirror Image World

The synthesis and a preliminary investigation of the base pairing properties of (6′ → 4′)-linked 1′,5′-anhydro-L-ribo-hexitol nucleic acids (α-L-HNA) have herein been reported through the study of a model oligoadenylate system in the mirror image world. D

Sodium borohydride-nickel chloride-methanol catalytic system for regioselective reduction of electron-rich conjugated dienes and reductive cleavage of allyl esters involving π-allylnickel intermediates

The regioslective reduction of electron-rich dienes to monoolefins and the reductive cleavage of allyl esters were fulfilled by employing a sodium borohydride-nickel chloride-methanol catalytic system with exceedingly simple manipulations and high functional group tolerability. Both of the reductive reactions may involve π-allylnickel intermediates generated from fresh nickel boride. Copyright

Selective Deoxygenation of Unsaturated Carbohydrates with Pd(0)/Ph2SiH2/ZnCl2. Total Synthesis of (+)-(S,S)-(6-Methyltetrahydropyran-2-yl)acetic Acid

Highly chemoselective reductive cleavage of allylic acetates of 1,2- and 2,3-unsaturated monosaccharides was achieved by a three-component reducing system comprised of diphenylsilane, a soluble palladium(0) catalyst, and catalytic amounts of zinc chloride.It was demonstrated that hydride substitution proceeds with absolute inversion of configuration at the carbon, implying that hydride is initially transferred to palladium and from there to the allylic ligand.The usefulness of the new chiral building blocks thus formed was demonstrated by the total synthesis of the civet constituent, (+)-(2S,6S)-cis-(6-methyltetrahydropyran-2-yl)acetic acid and its 2R,6S-trans isomer.