26560-38-3

Basic information

• Product Name: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)
• Synonyms: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1);Nsc173328;5-Methyltetrahydrofolate calcium;calciuM dihydride - N-[(4-{[(2-aMino-5-Methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)Methyl]aMino}phenyl)carbonyl]glutaMic acid;5-Methyltetrahydrofolate calciuM (raceMate);CalciuM N5-Methyltetrahydrofolate;Calcium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido);5-Methyl-6(RS)-tetrahydrofolate calciuM salt
• CAS NO: 26560-38-3
• Molecular Formula: C20H23CaN7O6
• Molecular Weight: 497.51792
• Mol File: 26560-38-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(26560-38-3)
• EPA Substance Registry System: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(26560-38-3)

Safety Data

• Hazardous Substances Data: 26560-38-3(Hazardous Substances Data)

Usage

description

Calcium N5-methyltetrahydrofolate is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.

Physical properties

5-methyltetrahydrofolate calcium is a white to slightly yellowish powder.

uses

5-methyltetrahydrofolate calcium belongs to organic calcium compounds and can act on cardiovascular disease, breast cancer, and colorectal cancer.Calcium N5-methyltetrahydrofolate is a metabolite of folic acid. It was shown to inhibit photosensitization reactions and strand breaks in DNA, and reduce total serum homocysteine level in orthotopic liver transplant recipients.

Sources

Calcium methyltetrahydrofolate is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt.

storage

5-methyltetrahydrofolate calcium can be storaged under room temperature away from light.

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

InChI:InChI=1/C20H25N7O6.Ca.2H/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;;;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);;;/q;+2;2*-1