265642-27-1Relevant academic research and scientific papers
Synthesis, Characterization, and Antimicrobial Activity of RhIIIand IrIIIN-Heterocyclic Carbene Piano-Stool Complexes
Bernier, Chad M.,Duchane, Christine M.,Falkinham, Joseph O.,Martinez, Justin S.,Merola, Joseph S.
, p. 1670 - 1681 (2021)
A series of RhIII and IrIII piano-stool complexes of the form [(ν5-Cp*R)M(NHC)Cl2] was synthesized and characterized, including 12 X-ray crystallographic structures. The antimicrobial properties of these complexes were screened against a variety of microbes, with several achieving high activities, most notably against Mycobacterium smegmatis (MICs as low as 0.45 μM). In general, the Rh complexes were more potent than their Ir analogues, and activity increased with the hydrophobicity of the Cp*R and NHC ligands.
Unsymmetrically substituted iridium(III)-carbene complexes by a CH-activation process
Prinz, Martina,Grosche, Manja,Herdtweck, Eberhardt,Herrmann, Wolfgang A.
, p. 1692 - 1694 (2008/10/08)
The synthesis of a new type of Ir-(III)-carbene complexes, Cp*(L′)IrH+OTf- (L′ = 1-(2-cyclohexenyl)-3-cyclohexylimidazolin-2-ylidene, OTf = OSO2CF3), based on the activation and subsequent functionalization of one cyclohexyl substituent at the N-heterocyclic carbene by a CH-activation/β-hydrogen migration process at the iridium(III) center was reported. The CH-activation/β-hydrogen migration process leads to the selective activation of one cyclohexyl ring at the N-heterocyclic carbene ligand.
