265643-71-8Relevant academic research and scientific papers
2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: Functionally selective GABAA α3-subtype agonists
Carling, Robert W.,Russell, Michael G.N.,Moore, Kevin W.,Mitchinson, Andrew,Guiblin, Alexander,Smith, Alison,Wafford, Keith A.,Marshall, George,Atack, John R.,Street, Leslie J.
, p. 3550 - 3554 (2007/10/03)
Novel synthetic routes have been devised for the preparation of previously inaccessible 2,3,7-trisubstituted pyrazolo[1,5-d][1,2,4]triazines 2. These compounds are high affinity ligands for the GABAA benzodiazepine binding site and some analogu
Pyrazolo-triazine derivatives as ligands for GABA receptors
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, (2008/06/13)
Compounds according to Formula (I): or a salt or prodrug thereof, have good affinity as ligands for the alpha2 and/or alpha3 subunit of the human GABAAreceptor and are useful for treatment of disorders of the central nervous system, including a
Pyrazolo[1,5-d][1,2,4] triazines for enhancing cognition
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, (2008/06/13)
Compounds according to Formula (I) or a salt thereof are GABA-A Alpha 5 ligands useful for enhancing cognition: STR1
