265643-91-2

Usage

Uses

Used in Pharmaceutical Development:
[1,2,4]triazolo[1,5-a]pyridin-2-ylmethanol is used as a key intermediate in the development of new drugs due to its unique structure and potential biological activity. Its ability to interact with various biological targets makes it a promising candidate for the creation of novel therapeutic agents.
Used in Medicinal Research:
In the field of medicinal research, [1,2,4]triazolo[1,5-a]pyridin-2-ylmethanol serves as a valuable compound for investigation. Its structure and properties allow researchers to explore its potential applications in treating various medical conditions and to understand its mechanisms of action.
Used in Drug Design:
[1,2,4]triazolo[1,5-a]pyridin-2-ylmethanol is used as a structural component in drug design, where its heterocyclic nature can be exploited to create molecules with specific biological activities. This can lead to the development of targeted therapies for a range of diseases and conditions.
Used in Chemical Synthesis:
As a chemical compound with a unique structure, [1,2,4]triazolo[1,5-a]pyridin-2-ylmethanol can be used as a building block in the synthesis of more complex molecules. This can be particularly useful in the creation of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in the Medical Industry:
[1,2,4]triazolo[1,5-a]pyridin-2-ylmethanol is used as a compound with potential therapeutic applications in the medical industry. Its biological activity and structural properties make it a valuable asset for the development of new treatments and therapies for various diseases and conditions.

Upstream product

• 62135-58-4 ethyl s-triazolo<1,5-a>pyridine-2-carboxylate 
• 96-35-5 glycolic acid methyl ester 
• 56000-35-2 1-aminopyridin-2(1H)-iminium-2,4,6-trimethylbenzenesulfonate 
• 504-29-0 2-aminopyridine 

Downstream Products

• 1373338-09-0 [1,2,4]Triazolo[1,5-a]pyridine-2-carbaldehyde 

Relevant academic research and scientific papers

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

PDE10 MODULATORS

The present invention relates to compounds of formula (I) wherein R1, R2, R3, R5, W, X, X1, Y, Y1, Z and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used in the treatment of CNS disorders such as schizophrenia, Alzheimer's disease, and Parkinson's disease.

PDE10 MODULATORS

The present invention relates to compounds of formula (I) wherein R1, R2, R3, R5, W, X, X1, Y, Y1, Z and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used as medicaments.

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

METABOTROPIC GLUTAMATE RECEPTOR MODULATORS

The invention relates to heterocyclic derivatives of formula (I) as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders wherein Y, W, R1, R2 and R3 are as defined in claim 1.

Pyrazolo-triazine derivatives as ligands for GABA receptors

Compounds according to Formula (I): or a salt or prodrug thereof, have good affinity as ligands for the alpha2 and/or alpha3 subunit of the human GABAAreceptor and are useful for treatment of disorders of the central nervous system, including a