265644-40-4Relevant academic research and scientific papers
First Highly Stereoselective Synthesis of Fungicide Systhane
Ruano, Jose L. Garcia,Garcia, Marta Cifuentes,Castro, Ana M. Martin,Ramos, Jesus H. Rodrigues
, p. 55 - 58 (2007/10/03)
Highly enantiopure (R)-2-p-chlorophenyl-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile 1 (myclobutanil or systhane) was obtained in six synthetic steps from commercially available 1-hexyne (35% yield, 92% ee). The sulfinyl group controls the two key steps o
Chemoenzymatic synthesis of optically active 2-phenyl-2-(1H-1,2,4- triazol-1-ylmethyl)hexanenitrile
Im, Dai Sig,Cheong, Chan Seong,Lee, So Ha,Youn, Byoung Hee,Kim, Seok Chan
, p. 1309 - 1314 (2007/10/03)
(±)-2-Cyano-2-phenyl-1-hexanol 3 was resolved to each enantiomer using Candida rugosa and Pseudomonas fluorescens lipases in 62 and 99% ee, respectively. The absolute stereochemistry of one of the enantiomers was determined to be (S) by diastereomeric ami
