26584-00-9Relevant academic research and scientific papers
Synthesis of Allenylphosphonates through Cu(I)-Catalyzed Coupling of Terminal Alkynes with Diazophosphonates
Wu, Chenggui,Ye, Fei,Wu, Guojiao,Xu, Shuai,Deng, Guisheng,Zhang, Yan,Wang, Jianbo
, p. 751 - 760 (2016/02/27)
Through the Cu(I)-catalyzed coupling of diazophosphonates with terminal alkynes, an efficient method for the synthesis of allenylphosphonates has been developed. Simple and inexpensive CuI is used as the catalyst and the reaction is conducted under mild conditions.
Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of α-Diazo Phosphonates with Benzyl or Allyl Halides
Zhou, Yujing,Ye, Fei,Wang, Xi,Xu, Shuai,Zhang, Yan,Wang, Jianbo
, p. 6109 - 6118 (2015/06/30)
An efficient method for the synthesis of organophosphonates through palladium-catalyzed coupling of α-diazo phosphonates with benzyl or allyl halides has been developed. Trisubstituted alkenylphosphonates bearing versatile functional groups can be easily accessed in good yields and with excellent stereoselectivity through this method. Moreover, with similar strategy α-substituted vinylphosphonates can also be attained by the palladium-catalyzed coupling reaction of N-tosylhydrazones and aryl bromides. Migratory insertion of palladium carbene is proposed as the key step in this reaction.
